Clinical Evidence

A prospective comparative evaluation was conducted involving 428 patients undergoing total hip or total knee arthroplasty. Patients received either the hospital's then-standard dressing regimen (Mepore™ dressing covering AQUACEL ® dressing), or a modified dressing regimen of AQUACEL ® dressing covered with DuoDERM® Extra Thin dressing (the main components of AQUACEL™ SURGICAL Cover dressing) after application of a liquid film-forming acrylate. The modified dressing regimen was not enhanced by the addition the acrylate.1


  Modified dressing design Standard technique p-value1
N 242 186  
Superficial surgical site infection 1% 3% <0.03


2% 18% <0.001
Mean wear time (days) 3.7 2.3 <0.001
Mean no. of dressing changes 1.5 3.2 <0.001
Delayed discharge 1% 5% <0.02

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