AQUACEL® Ag dressing

 

 

The clinical behaviour of these dressings "showed a strong resemblance with cadaver skin treatment with respect to adherence to the wound". a, 4

*Artist's interpretation

AQUACEL ® Ag Dressing, incorporating Hydrofiber® Technology with ionic silver, is indicated for partial-thickness burns that are infected or are at an elevated risk of infection (e.g., large partial thickness burns).

HOW THE DRESSING WORKS ON BURNS

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AQUACEL ® Ag Dressing is intended to adhere to a partial thickness burn through the collection of fibrin, which forms between the dressing and the wound surface.a,1,2,3

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The dressing will detach itself from the wound surface once re-epithelialisation has occurred.a,4


AQUACEL ® Ag Dressing has demonstrated a number of properties which are beneficial for the management of superficial and mid-dermal partial thickness burns.3,4

  • Reduced pain and discomfort during dressing changes
  • Can be left in place for up to 14 days
  • Few dressing changes
  • Ease of application

In vitro studies with AQUACEL ® Ag Dressing have demonstrated microbicidal activity against a wide range of pathogens up to a period of 14 days.6

CLINICAL STUDY RESULTS

Caruso, et al. 2006

In a randomised clinical study of AQUACEL ® Ag Dressing versus silver sulfadiazine, AQUACEL ® Ag Dressing was associated with:5

  • Significantly less pain and anxiety during dressing changes (P=0.002 and P=0.009, respectively)
  • Fewer dressing changes and less nursing time (P<0.001)
  • Fewer procedural and opiate medications during dressing changes
  • Lower average total cost of care per burn healed versus silver sulfadiazine cream

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  • Less than half the number of dressing changes as silver sulfadiazine
  • Significantly less nursing timeper dressing change
  • 28% reduction in the cost per partial thickness burn healed compared to silver sulfadiazine
  • Lower total treatment cost for a 21-day regimen (including dressings medication and labour):

Caruso, et al. 2004

In a phase II non-comparative trial of AQUACEL ® Ag Dressing in superficial, mid-dermal and mixed partial-thickness burns:2

  • The ability of AQUACEL ® Ag Dressing to soothe pain was rated as "excellent" or "very good" in 91% of patients by the investigator at final assessment
  • There was a significant reduction in pain whilst the dressing was in situ between baseline and day-3 and baseline and day-5 (P=0.0006 and P=0.0256, respectively)
  • "77% [of] patients achieved complete healing ... within 14 days ... [with] ... AQUACEL® Ag [dressing]"
  • "[With AQUACEL® Ag] the dressing/wound interface remains moist, thereby ... [supporting] ... an appropriate environment for re-epithelialisation of the superficial and mid-dermal areas"

Paddock, et al. 2007

In a retrospective review of data on pediatric patients treated with AQUACEL ® Ag Dressing versus silver sulfadiazine:7

  • Total and direct hospital costs per treated patient were significantly lower for AQUACEL ® Ag Dressing(P<0.001 and P=0.004, respectively)
    • Fixed and variable costs for AQUACEL® Ag totaled: $2,594
    • Fixed and variable costs for silver sulfadiazine totalled: $6,389
    • "application of ... ( AQUACEL ® Ag Dressing) reduces both total charges and direct costs for paediatric patients admitted with partial-thickness burn wounds."

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